A USB host card is an interface that allows an enabled piece of hardware to interact and communicate with a particular piece of software. The USB connection is an input and output port that comes standard with most computers and a variety of other digital equipment that allows data to be transmitted through a cable or any other form of direct connection. A USB host card manages the communication between peripheral devices and the computer system. Most modern computers have hi-speed USB ports and many older computers can have a USB host card easily installed in an open slot on its motherboard.